ReproBone™ bone graft
substitutes are manufactured
in granular and paste forms.
The chemical composition of their matrices is very similar to that found in human cancellous bone and acts as an ideal scaffold for bone support and regeneration.
Copyright Ceramisys 2011
BONE GRAFT SUBSTITUTE
CLINICAL PERFORMANCE
ReproBone™ Blocks / Granules / Discs / Wedges
ReproBone™ has proven biocompatibility and
osteoconductivity. Studies show that ReproBone™
implanted both in cancellous bone and cortical
bone provides excellent osseointegration with
rapid bone penetration through to the core of
the implant.
1. OSTEOCONDUCTION Bone radiating through pores to the centre of the implant.
2. INTEGRATION At 12 weeks complete integration with new bone, implant is now embedded within new bone forming bicontinuous matrix.
3. CONSOLIDATION & MATURATION Osteoclastic resorption and phagocytosis, releases calcium and phosphate ions locally, which in turn encourages osteoblastic activity and the deposition of new bone. Bone remodelling transforms initially woven bone into lamellar bone.
4. RESORPTION At 12 weeks osteoclastic resorption can be clearly observed, the implant has a distinctly blurred outline with highly microporous surface. Bone remodelling continues until the implant is completely resorbed.
