ReproBone™ bone graft
substitutes are manufactured in granular and paste forms.
The chemical composition of their matrices is very similar to that found in human cancellous bone and acts as an ideal scaffold for bone support and regeneration.

BONE GRAFT SUBSTITUTE

SYNTHETIC
Innovative products that offer a sterile, reliable alternative to cancellous autograft, xenograft or allograft that are available in unlimited quantities.

SAFE AND RELIABLE
A gamma sterilised product, available in unlimited quantities. The biocompatibility and clinical efficacy of HA and ß-TC P as bone substitute materials is supported by over 3000 publications and over 500 clinical studies with 25 years of successful use.

REDUCED MORBIDITY
With healing times comparable to that of autogeneous and xenograft bone grafts, ReproBone™ is the natural alternative to bone grafts, in many cases eliminating the need for a second operation site, reducing blood loss and lowering patient morbidity.

PROVEN TECHNOLOGY THE WORLD OVER
Over the last 20 years, hundreds of successful clinical studies have been performed on the ability of porous HA and TC P to provide an osteoconductive environment assisting in the regeneration of a bony defect. A biphasic HA/TC P composition with a highly interconnected structure provides optimal osteoconductivity. The ReproBone novo™ composition with water provides an effective osteostimulative environment for bone regeneration. Due to their similarity with human bone, no adverse reactions have ever been reported. The calcium and phosphate resorption products are beneficial in assisting local osteoblast activity at the site.

ReproBone™
Blocks / Granules / Discs / Wedges

READY TO USE
Pre-shaped in standard sizes, sterile and easy to handle.

EASY APPLICATION
ReproBone™ blocks can be soaked with blood, or bone marrow aspirate e.g. for spinal fusion procedures, and can easily be cut and shaped to fit the defect. ReproBone™ granules when mixed with blood, bone marrow aspirate or platelet concentrate form a cohesive mixture that is easily handled. Can be mixed with autograft as a bone graft extender if required.

INDICATIONS
ReproBone™ blocks and granules are indicated for use as a bone graft substitute for the repair of non-load bearing osseous defects. Standard fixation techniques must be used in load bearing applications. Resorbable 60% HA , 40% ß-TC P composition is similar to the mineral component of human bone and undergoes complete resorption at a controlled rate.

ULTRA HIGH POROSITY
Over 80% porosity allows rapid bone ingrowth throughout the pores. ReproBone™ provides support without significantly limiting natural bone density. Microporosity within the HA/TC P structure assists the transfer of essential nutrients.

OSTEOCONDUCTIVE
Osteoconductive scaffold. Vascularisation and fast bone regeneration throughout the implant occurs within a few months.

CLINICAL PERFORMANCE + PROPERTIES