ReproBone™ bone graft
substitutes are manufactured
in granular and paste forms.
The chemical composition of their matrices is very similar to that found in human cancellous bone and acts as an ideal scaffold for bone support and regeneration.
Copyright Ceramisys 2011
BONE GRAFT SUBSTITUTE
PASTE PERFORMANCE
ReproBone novo™ Nanocrystalline Synthetic Bone Graft Paste
ReproBone novo™ has proven biocompatibility and
bone regenerative properties. Studies show that
ReproBone novo™ implanted in cancellous bone
provides excellent osseointegration with rapid
vascularisation and bone penetration through to
the core of the implant.
1. APPLICATION & PRIMARY STAGES The non-hardening mouldable paste does not form a barrier
to adjacent healthy bone cells, the sticky paste ensures good
contact and cells readily migrate inwards. Blood passively
infiltrates, bringing with it the growth factors needed for bone
regeneration, and early vascularisation takes place.
2. BONE FORMATION ReproBone novo™ stimulates bone healing by accelerating
the rate at which bone-forming cells proliferate, resulting in a
rapid building of new bone.
The bone defect is regenerated with new woven bone after
several weeks. In parallel the graft has been almost completely
resorbed by macrophages and osteoclasts. Remodelling and
maturation of the bone continues as normal.
