ReproBone™ bone graft
substitutes are manufactured in granular and paste forms.
The chemical composition of their matrices is very similar to that found in human cancellous bone and acts as an ideal scaffold for bone support and regeneration.

BONE GRAFT SUBSTITUTE PASTE

SYNTHETIC
Innovative products that offer a sterile, reliable alternative to cancellous autograft, xenograft or allograft that are available in unlimited quantities.

SAFE AND RELIABLE
A gamma sterilised product, available in unlimited quantities. The biocompatibility and clinical efficacy of HA and ß-TC P as bone substitute materials is supported by over 3000 publications and over 500 clinical studies with 25 years of successful use.

REDUCED MORBIDITY
With healing times comparable to that of autogeneous and xenograft bone grafts, ReproBone™ is the natural alternative to bone grafts, in many cases eliminating the need for a second operation site, reducing blood loss and lowering patient morbidity.

PROVEN TECHNOLOGY THE WORLD OVER
Over the last 20 years, hundreds of successful clinical studies have been performed on the ability of porous HA and TC P to provide an osteoconductive environment assisting in the regeneration of a bony defect. A biphasic HA/TC P composition with a highly interconnected structure provides optimal osteoconductivity. The ReproBone novo™ composition with water provides an effective osteostimulative environment for bone regeneration. Due to their similarity with human bone, no adverse reactions have ever been reported. The calcium and phosphate resorption products are beneficial in assisting local osteoblast activity at the site.

ReproBone novo™
Nanocrystalline Synthetic Bone graft paste

READY TO USE
Easy to use with no pre-mixing or preparation required. Remove cap and apply directly from the applicator.

STICKY MOULDABLE PASTE CONSISTENCY
Sticky viscosity allows easy positioning, adapts easily to the shape of the defect. Sticks to the bone surface maximising the bone-implant interface.

VOLUME STABLE
Stays inside the defect and resists irrigation. Blood will eventually impregnate the implant and resettle the growth factors essential for bone regeneration. Vascularisation will impregnate the implant, laying the foundation support essential for bone regeneration.

NANO TECHNOLOGY
With a high molecular surface area of the Hydroxyapatite approx 100M2 per cc for ReproBone novo™ it is 50-100 times greater than typical bone graft technologies.

RESORBABLE
The nano HA composition undergoes complete resorption over a period of months.

AQUEOUS PASTE
The sticky aqueous composition of nano HA and water does not form a barrier to vascularisation or bone colonisation and allows rapid bone ingrowth throughout the material. The product provides support without significantly limiting natural bone density.

POSITIVE OSTEOSTIMULATIVE EFFECT
The high molecular surface area attracts natural bone growth promoters to adsorb onto the surface and contributes towards the osteostimulative effect. The dissolution by products contribute to locally elevated Ca and P ions encouraging remineralisation. Early vascularisation takes place and fast bone regeneration throughout the implant occurs within a few months.

CLINICAL PERFORMANCE + PROPERTIES